Wilson Street will be closed between Gordon Street and Northumberland Street, starting this morning, for the next couple of months.
The city is installing new storm and sanitary sewers and water mains.
This is the first phase of the Wilson Street parkade project.
The city says every effort will be made to maintain access to the Wilson Street parking lot.
It may be necessary to close the parking lot for certain construction activities.
When this happens, the city promises that permit holders will be notified ahead of time.
Guelph Transit routes 5, 8 and 9 will be detoured during the construction.
And from 7 this morning until about 4 in the afternoon, the southbound lanes of Edinburgh Road between Waterloo Avenue and Paisley Road will closed as the city does some water works repairs.